Solve your most complex genomes
Dovetail’s linked-read chemistry allows for flexible capture of both large genomic changes like translocations all the way down to single nucleotide variants. Our high resolution genomic data output uncovers somatic variations, 3D chromatin architecture, and achieves haplotype-resolved assembly with a single assay.
LinkPrep for
One assay for all your chromatin research questions
A complete solution—sample to sequence to insight, we have you covered with our team of support scientists and our bioinformatics portal.
What is a linked-read?
Linked-read is a term for any genomic sequencing output that has additional oligo information. Other examples of types of linked-reads include droplet single cell sequencing for determining single cell genomic information or tell-seq for looking at single molecule information.
Dovetail Genomic’s linked-read assays focus on the positional DNA-DNA relationship and include proximity ligation oligo information to provide spatial information about the DNA in the nucleus.
Why Dovetail linked-read?
Linked-read sequencing overcomes the linear limitations of short-read approaches to enable detection of long-range information including structural variations, haplotype resolution, and unbiased 3D genomics—without sacrificing sequencing depth or data quality.
A legacy of solving complex genomic problems
Dovetail Genomics started in 2013 with HiRise, a revolutionary Hi-C assay that achieved the highest-resolution genome assemblies of any assay. With Micro-C and Omni-C, Dovetail made great advancements in genome libraries, through unbiased chromosome digestion and proximity ligation. Since then Dovetail has remained committed to innovation and uncovering all the mysteries of the genome, expanding into more applications even faster than before, with its single-day assay; LinkPrep technology.