For those looking for the ultimate scaffolding tool, Dovetail Omni-C data delivers uniform, shotgun-like sequence coverage enabling genotyping and haplotype phasing, alongside long-range information characteristic of Hi-C data. Take your assembly to the next level with a fully haplotype-resolved genome.
Haplotype-resolved assembly provides a complete picture of genomes and genetic variations. Most of the existing assembly algorithms either provide haplotype collapsed assembly or require pedigree information for phasing. New long-range sequencing approaches, such as PacBio’s HiFi technology , combined with Dovetail Omni-C libraries, a proximity ligation technology that captures chromosome-scale interactions with uniform sequencing coverage comparable to traditional shotgun sequencing libraries, make full chromosome scale haplotype resolved genome assemblies possible.